Mebeverine 135 mg: Uses, Dosage, Side Effects, Safety, and Frequently Asked Questions
What Is Mebeverine 135 mg?
Mebeverine 135 mg is a prescription and pharmacy medicine used to relieve symptoms associated with irritable bowel syndrome (IBS) and other intestinal conditions involving painful bowel spasms.
It belongs to a group of medicines called antispasmodics. Mebeverine works by relaxing the muscles of the intestine, helping reduce uncomfortable bowel contractions without stopping normal bowel movement.
Mebeverine is available as:
- 135 mg tablets
- Modified-release capsules (commonly 200 mg in some countries)
How Mebeverine Works

The intestines contain smooth muscles that contract to move food through the digestive system. In conditions such as IBS, these muscles can contract excessively, causing cramps and discomfort.
Mebeverine works by:
- Relaxing intestinal smooth muscle.
- Reducing painful bowel spasms.
- Helping relieve abdominal cramping.
- Allowing the bowel to function more comfortably.
Unlike some other antispasmodics, mebeverine generally does not significantly affect normal bowel movement.
Mebeverine 135 mg Uses
Irritable Bowel Syndrome (IBS)
Mebeverine is commonly used to manage symptoms of IBS, including:
- Stomach cramps.
- Abdominal pain.
- Bloating.
- Excessive intestinal spasms.
- Changes in bowel habits such as diarrhea or constipation associated with IBS.
Other Intestinal Spasm Conditions
Healthcare providers may sometimes recommend mebeverine for other bowel conditions involving spasms, depending on the individual situation.
Benefits of Mebeverine 135 mg
When used appropriately, mebeverine may help:
- Reduce painful abdominal cramps.
- Relax overactive bowel muscles.
- Improve digestive comfort.
- Reduce discomfort associated with IBS symptoms.
- Support better daily functioning for people with bowel spasms.
Mebeverine 135 mg Dosage
The correct dose depends on the product and individual needs.
General guidance:
- The usual adult dose for 135 mg tablets is one tablet three times daily.
- Take it as directed by your healthcare provider or according to the product instructions.
- It is usually taken before meals.
- Do not exceed the recommended dose.
If symptoms improve, your healthcare provider may advise reducing or stopping treatment.
How to Take Mebeverine 135 mg
For best results:
- Take the tablet about 20 minutes before meals if instructed.
- Swallow tablets with water.
- Do not crush or chew modified-release forms.
- Follow the recommended schedule consistently.
Missed Dose
If you miss a dose:
- Take it when you remember if it is not close to your next dose.
- Skip the missed dose if it is nearly time for the next one.
- Do not take two doses together.
Common Side Effects
Mebeverine is generally well tolerated. Possible side effects may include:
- Mild nausea.
- Indigestion.
- Constipation.
- Dizziness.
- Headache.
Serious Side Effects
Serious side effects are uncommon, but seek medical attention if you experience signs of an allergic reaction, such as:
- Skin rash.
- Itching.
- Swelling of the face, lips, tongue, or throat.
- Difficulty breathing.
Safety Information
Before taking mebeverine, tell your healthcare provider if you have:
- Severe constipation.
- Blood in stools.
- Unexplained weight loss.
- Persistent vomiting.
- Fever.
- A history of bowel obstruction.
- Pregnancy or breastfeeding.
New or unexplained bowel symptoms should be medically assessed before assuming they are caused by IBS.
Drug Interactions
Mebeverine has relatively few known drug interactions.
However, always inform your healthcare provider about:
- Prescription medicines.
- Over-the-counter medicines.
- Vitamins.
- Herbal supplements.
Food and Alcohol
Mebeverine is usually taken before meals.
There is no major known direct interaction with alcohol, but excessive alcohol consumption may worsen digestive symptoms in some people.
Pregnancy and Breastfeeding
If you are pregnant, planning pregnancy, or breastfeeding:
- Speak with your healthcare provider before taking mebeverine.
- Your healthcare provider will decide whether it is suitable based on your individual circumstances.
Storage
Store mebeverine tablets:
- At room temperature.
- Away from moisture and heat.
- In the original packaging.
- Out of reach of children.
Do not use after the expiry date.
Frequently Asked Questions (FAQs)
What is Mebeverine 135 mg used for?
Mebeverine 135 mg is mainly used to relieve abdominal cramps, spasms, and discomfort caused by irritable bowel syndrome (IBS).
Is mebeverine a laxative?
No. Mebeverine is not a laxative. It is an antispasmodic medicine that relaxes bowel muscles.
How long does mebeverine take to work?
Some people notice improvement within a few hours, while others may need several days of regular use before symptoms improve.
Can I take mebeverine every day?
Yes, some people take mebeverine regularly for IBS symptoms, but follow your healthcare provider’s advice.
Can mebeverine stop diarrhea?
Mebeverine does not directly treat diarrhea. However, by reducing bowel spasms, it may help relieve cramping associated with IBS-related diarrhea.
Can mebeverine help constipation?
Mebeverine may help discomfort caused by bowel spasms but does not act as a constipation treatment.
Can I take mebeverine with other IBS medicines?
It may be combined with other treatments depending on your symptoms. Ask your healthcare provider before combining medicines.
Is mebeverine safe for long-term use?
Many people use mebeverine for longer periods under medical guidance, especially for recurring IBS symptoms.
Can children take mebeverine 135 mg?
Use in children depends on age and medical advice. Follow product instructions or healthcare guidance.
What happens if I take too much mebeverine?
Taking more than recommended may cause symptoms such as nausea, dizziness, or other discomfort. Seek medical advice if you take an excessive amount.
Final Thoughts
Mebeverine 135 mg is an antispasmodic medication commonly used to relieve painful intestinal spasms and symptoms associated with irritable bowel syndrome. It works by relaxing bowel muscles, helping reduce cramps and abdominal discomfort.
For the best results, take mebeverine as directed, maintain healthy digestive habits, and seek medical advice if symptoms are severe, persistent, or different from your usual IBS symptoms.
Medical Disclaimer: This article is for educational and informational purposes only and should not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.




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